Health_ontology

Last uploaded: July 4, 2024
Preferred Name

Ofloxacin
Synonyms

(+-)-ofloxacin

racemic ofloxacin

(3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

ofloxacinum

rac-ofloxacin

rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

DL 8280

DL-8280

Exocin

Floxin

Gailuoxian

HOE 280

HOE-280

OFLX

ORF 18489

Ocuflox

Oxaldin

Prifloxcin

Prifloxin

Tarivid

Visiren

ofloxacin

ofloxacine

ofloxacino

rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Definitions

A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

ID

http://purl.obolibrary.org/obo/CHEBI_7731

alternative label

(+-)-ofloxacin

racemic ofloxacin

(3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

ofloxacinum

rac-ofloxacin

rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

DL 8280

DL-8280

Exocin

Floxin

Gailuoxian

HOE 280

HOE-280

OFLX

ORF 18489

Ocuflox

Oxaldin

Prifloxcin

Prifloxin

Tarivid

Visiren

ofloxacin

ofloxacine

ofloxacino

rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

charge

0

database_cross_reference

PMID:36268299

PMID:15008519

KEGG:C07321

PMID:11903499

PMID:7884650

KEGG:D00453

Wikipedia:Ofloxacin

PMID:6960805

MetaCyc:CPD-12843

CAS:82419-36-1

PMID:1804789

DrugBank:DB01165

PMID:3469159

PMID:35897550

Drug_Central:1981

PMID:9228220

PMID:11710934

PMID:3546152

PMID:36004580

LINCS:LSM-4370

PMID:15557076

HMDB:HMDB0015296

PMID:36228398

PMID:19646516

PMID:24550337

PMID:16669862

PMID:12827054

Reaxys:3657947

PMID:24497308

VSDB:1898

definition

A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

formula

C18H20FN3O4

has exact synonym

rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

has part

http://purl.obolibrary.org/obo/CHEBI_63598

http://purl.obolibrary.org/obo/CHEBI_46577

has role

http://purl.obolibrary.org/obo/CHEBI_59517

http://purl.obolibrary.org/obo/CHEBI_50750

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_53559

has_alternative_id

CHEBI:100146

has_obo_namespace

chebi_ontology

has_related_synonym

(+-)-ofloxacin

racemic ofloxacin

(3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

ofloxacinum

rac-ofloxacin

rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

DL 8280

DL-8280

Exocin

Floxin

Gailuoxian

HOE 280

HOE-280

OFLX

ORF 18489

Ocuflox

Oxaldin

Prifloxcin

Prifloxin

Tarivid

Visiren

ofloxacin

ofloxacine

ofloxacino

has_RxCUI

7623

id

CHEBI:7731

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

label

Ofloxacin

ofloxacin

mass

361.373

monoisotopicmass

361.14378

notation

CHEBI:7731

prefLabel

Ofloxacin

subClassOf

http://purl.obolibrary.org/obo/CHEBI_87211

http://purl.obolibrary.org/obo/CHEBI_60911

http://purl.obolibrary.org/obo/CHEBI_86324

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http://purl.obolibrary.org/obo/CHEBI_7731 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 ODNAE SAME_URI
http://purl.bioontology.org/ontology/PDQ/CDR0000042865 PDQ LOOM
http://purl.obolibrary.org/obo/OMIT_0016032 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008462 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Ofloxacin GALEN LOOM
http://purl.jp/bio/4/id/200906021484962719 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C712 BERO LOOM
https://go.drugbank.com/drugs/DB01165 MDM LOOM
http://purl.bioontology.org/ontology/ATC/J01MA01 ATC LOOM
http://stirdf.jst.go.jp/id/200907089521022516 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.500 RH-MESH LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Ofloxacin SEPON LOOM
http://www.drugbank.ca/drugs/DB01165 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 ODNAE LOOM
http://purl.bioontology.org/ontology/LNC/LP16182-5 LOINC LOOM
http://purl.bioontology.org/ontology/SNMI/C-55790 SNMI LOOM
http://purl.bioontology.org/ontology/ATC/S02AA16 ATC LOOM
http://purl.bioontology.org/ontology/NDDF/003563 NDDF LOOM
http://purl.obolibrary.org/obo/ARO_3000663 ARO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028902 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147667 NDFRT LOOM
http://purl.bioontology.org/ontology/RCD/eg8.. RCD LOOM
http://purl.bioontology.org/ontology/VANDF/4019567 VANDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017912 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/ATC/S01AE01 ATC LOOM
http://purl.obolibrary.org/obo/MESH_D015242 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387551000 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8915 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/7623 RXNORM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C712 NCIT LOOM
http://purl.bioontology.org/ontology/MESH/D015242 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015242 RH-MESH LOOM