Cigarette Smoke Exposure Ontology

Last uploaded: July 10, 2014
Preferred Name

Comet assay

Synonyms
ID

http://scai.fraunhofer.de/CSEO#CSEO_00001555

isDefinedBy

A rapid, simple, visual and sensitive technique for measuring DNA breakage in individual mammalian cells in response to a test agent. A cell is immobilized in agarose and made permeable and the broken DNA migrates out under the influence of the electric field. A damaged cell has the appearance of a comet with a brightly fluorescent cell body and a tail whose length and fluorescence intensity are related to the number of DNA-strand breaks induced by the test agent.

label

Comet assay

prefixIRI

CSEO_00001555

prefLabel

Comet assay

Reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Single_Cell_Gel_Electrophoresis

Synonym

COMET

Single Cell Gel Electrophoresis

subClassOf

http://scai.fraunhofer.de/CSEO#CSEO_00001551

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