loading...| Preferred Name |
Interferon |
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| Synonyms |
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| ID |
http://scai.fraunhofer.de/CSEO#CSEO_00000878 |
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| isDefinedBy |
Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570), |
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| label |
Interferon |
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| prefixIRI |
CSEO_00000878 |
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| prefLabel |
Interferon |
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| Reference |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Interferon) |
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| source |
http://purl.bioontology.org/ontology/LNC/LP16468-8 http://www.stanford.edu/~coulet/phare.owl#Interferon http://purl.bioontology.org/ontology/NDFRT/N0000022612 http://purl.bioontology.org/ontology/CSP/1553-6680 http://purl.obolibrary.org/obo/IMR_0000027 http://purl.bioontology.org/ontology/SNOMEDCT/49327004 http://www.co-ode.org/ontologies/galen#Interferon http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Interferon |
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| Synonym |
Human Leukocyte Interferon IFN Human Lymphoblastoid Interferon Human Fibroblast Interferon |
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| subClassOf |