Cigarette Smoke Exposure Ontology

Last uploaded: July 10, 2014
Preferred Name

Gastrointestinal Tract Adenoma

Synonyms
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Gastrointestinal_Adenoma

DEFINITION

A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.

FULL_SYN

Gastrointestinal Adenoma

GI Adenoma

isDefinedBy

A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.

label

Gastrointestinal Tract Adenoma

prefixIRI

Thesaurus:Gastrointestinal_Adenoma

prefLabel

Gastrointestinal Tract Adenoma

Synonym

Gastrointestinal Adenoma

GI Adenoma

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Gastrointestinal_Neoplasm

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Adenoma

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