Cigarette Smoke Exposure Ontology

Last uploaded: July 10, 2014

Preferred Name	Classical Hodgkin Lymphoma
Synonyms
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Classical_Hodgkin_s_Lymphoma
DEFINITION	A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterized by a bimodal age distribution (15-30 years of life and late life) and is often associated with EBV infection. In less than 5% of cases it is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterized by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases.
FULL_SYN	Classical Hodgkin's Lymphoma CHL
isDefinedBy	A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterized by a bimodal age distribution (15-30 years of life and late life) and is often associated with EBV infection. In less than 5% of cases it is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterized by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases.
label	Classical Hodgkin Lymphoma
prefixIRI	Thesaurus:Classical_Hodgkin_s_Lymphoma
prefLabel	Classical Hodgkin Lymphoma
Synonym	Classical Hodgkin's Lymphoma CHL
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Hodgkin_s_Lymphoma

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SNOMEDCT/762690000	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/762691001	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/MEDDRA/10080208	MEDDRA	LOOM