COVID-19 Ontology

Last uploaded: February 25, 2021
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Preferred Name

omacetaxine mepesuccinate
Synonyms

(-)-homoharringtonine

Homoharringtonine

omacetaxini mepesuccinas

(2'R,3S,4S,5R)-(-)-homoharringtonine

mepesuccinate d'omacetaxine

omacetaxine mepesuccinate

mepesuccinato de omacetaxina

CGX-635

Synribo
Definitions

A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.
ID

http://purl.obolibrary.org/obo/CHEBI_71019
charge

0
database_cross_reference

PMID:23086639

PMID:23109844

PMID:21415308

PMID:23059828

PMID:21509439

PMID:22714632

PMID:21152934

PMID:23053254

PMID:22075327

PMID:21468038

Drug_Central:4677

PMID:21418889

PMID:22917222

PDBeChem:HMT

PMID:22898909

PMID:21258877

PMID:22289991

PMID:21294709

PMID:21916787

LINCS:LSM-3716

KEGG:D08956

PMID:22967374

Patent:WO2007089878

Reaxys:5687925

Patent:US2010240887

Beilstein:5687925

PMID:22054289

PMID:22391162

PMID:22896000

PMID:22040954

PMID:21845438

CAS:26833-87-4

PMID:22580751

PMID:23456623

PMID:20971952

Wikipedia:Omacetaxine_mepesuccinate
definition

A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.
formula

C29H39NO9
fromPubMed

true
has_obo_namespace

chebi_ontology
has_related_synonym

(-)-homoharringtonine

Homoharringtonine

omacetaxini mepesuccinas

(2'R,3S,4S,5R)-(-)-homoharringtonine

mepesuccinate d'omacetaxine

omacetaxine mepesuccinate

mepesuccinato de omacetaxina

CGX-635

Synribo
id

CHEBI:71019
imported from

http://purl.obolibrary.org/obo/chebi.owl
in_subset

http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR
inchi

InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1
inchikey

HYFHYPWGAURHIV-JFIAXGOJSA-N
label

omacetaxine mepesuccinate
mass

545.62130
monoisotopicmass

545.26248
notation

CHEBI:71019
oboInOwl:hasDbXRef

https://www.ncbi.nlm.nih.gov/pubmed/32251767
preferred label

omacetaxine mepesuccinate
prefLabel

omacetaxine mepesuccinate
smiles

[H][C@@]12[C@H](OC(=O)[C@@](O)(CCCC(C)(C)O)CC(=O)OC)C(OC)=C[C@@]11CCCN1CCc1cc3OCOc3cc21
textual definition

A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.
subClassOf

http://purl.obolibrary.org/obo/CHEBI_23888
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_71019 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 INBANCIDO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 CIDO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_71019 OBA SAME_URI
http://purl.bioontology.org/ontology/PDQ/CDR0000039476 PDQ LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_71019 OBA LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/421815001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4031782 VANDF LOOM
http://purl.obolibrary.org/obo/DRON_00018264 INBANCIDO LOOM
http://purl.obolibrary.org/obo/DRON_00018264 CIDO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039476 PDQ LOOM
http://purl.bioontology.org/ontology/NDDF/009753 NDDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000186058 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/L01XX40 ATC LOOM
https://go.drugbank.com/drugs/DB04865 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1127 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026211 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/27100 RXNORM LOOM
http://purl.obolibrary.org/obo/NCIT_C1127 BERO LOOM