Coronavirus Infectious Disease Ontology

Last uploaded: February 16, 2024
Preferred Name

lycorine
Synonyms

Galanthidine

(-)-lycorine

Amarylline

Licorine

Narcissine

9,10-(methylenedioxy)-3,12-didehydrogalanthan-1alpha,2beta-diol

Lycorine

Definitions

An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity.

ID

http://purl.obolibrary.org/obo/CHEBI_6601

alternative term

Galanthidine

(-)-lycorine

Amarylline

Licorine

Narcissine

9,10-(methylenedioxy)-3,12-didehydrogalanthan-1alpha,2beta-diol

Lycorine

charge

0

chemical effective in vitro against virus

http://purl.obolibrary.org/obo/NCBITaxon_1335626

chemical inhibits in vitro replication of virus

http://purl.obolibrary.org/obo/NCBITaxon_1335626

database_cross_reference

PDBeChem:3KD

PMID:15386196

Beilstein:93605

PMID:14669261

PMID:12232602

KEGG:C08532

CAS:476-28-8

KNApSAcK:C00001576

PMID:19788245

Reaxys:93605

definition source

PMID: 30918074

formula

C16H17NO4

has exact synonym

9,10-(methylenedioxy)-3,12-didehydrogalanthan-1alpha,2beta-diol

Lycorine

has parent hydride

http://purl.obolibrary.org/obo/CHEBI_35646

has role

http://purl.obolibrary.org/obo/CHEBI_76924

http://purl.obolibrary.org/obo/CHEBI_149553

http://purl.obolibrary.org/obo/CHEBI_48001

http://purl.obolibrary.org/obo/CHEBI_38068

has_obo_namespace

chebi_ontology

has_related_synonym

Galanthidine

(-)-lycorine

Amarylline

Licorine

Narcissine

id

CHEBI:6601

imported from

http://purl.obolibrary.org/obo/chebi.owl

in subset

http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR

inchi

InChI=1S/C16H17NO4/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19/h3-5,11,14-16,18-19H,1-2,6-7H2/t11-,14-,15+,16+/m0/s1

inchikey

XGVJWXAYKUHDOO-DANNLKNASA-N

label

lycorine

mass

287.31050

monoisotopicmass

287.11576

notation

CHEBI:6601

prefLabel

lycorine

smiles

[H][C@]12[C@H](O)[C@@H](O)C=C3CCN(Cc4cc5OCOc5cc14)[C@@]23[H]

textual definition

An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity.

subClassOf

http://purl.obolibrary.org/obo/CHEBI_38511

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