loading...| Preferred Name | Ivermectin | |
| Synonyms |
ivermectinum ivermectino ivermectine Privermectin Ivermax Ivomec Mectizan Noromectin Sklice Stromectol Vetrimec Zimecterin ivermectin |
|
| Definitions |
A mixture consisting of >= 80% 22,23-dihydroavermectin B1a and <= 20% 22,23-dihydroavermectin B1b. It is a semi-synthetic derivative of abamectin. A broad-spectrum antiparasite medication, particularly against worms (except tapeworms) but also effective againstmost mites and some lice A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6078 |
|
| alternative term |
ivermectinum ivermectino ivermectine Privermectin Ivermax Ivomec Mectizan Noromectin Sklice Stromectol Vetrimec Zimecterin ivermectin |
|
| charge |
0 |
|
| chemical effective in vitro against virus | ||
| chemical has protein target | ||
| chemical has protein target as agonist | ||
| chemical inhibits in vitro replication of virus | ||
| database_cross_reference |
PMID:21824728 Chemspider:7988461 KEGG DRUG:D00804 PMID:22047763 CiteXplore:22039801 Wikipedia:Ivermectin PMID:15078277 CiteXplore:21824728 KEGG COMPOUND:C07970 DrugBank:DB00602 PMID:18718154 CiteXplore:18718154 ChemIDplus:70288-86-7 CiteXplore:15078277 KEGG:D00804 KEGG COMPOUND:70288-86-7 PMID:22039784 Patent:US4199569 CAS:70288-86-7 Pesticides:ivermectin CiteXplore:21831526 PMID:21831526 PMID:22039801 CiteXplore:22047763 VSDB:1455 |
|
| definition source |
https://www.drugbank.ca/drugs/DB00602 Doi: 10.1016/S0140-6736(20)31042-4 |
|
| formula |
C48H74O14.C47H72O14 C47H71O14R |
|
| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_24852 http://purl.obolibrary.org/obo/CHEBI_35820 http://purl.obolibrary.org/obo/CHEBI_73333 |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
ivermectinum ivermectino ivermectine Privermectin Ivermax Ivomec Mectizan Noromectin Sklice Stromectol Vetrimec Zimecterin ivermectin |
|
| has_RxCUI |
6069 |
|
| id |
CHEBI:6078 |
|
| imported from | ||
| in subset | ||
| label |
Ivermectin ivermectin |
|
| mass |
860.060 |
|
| monoisotopicmass |
859.48438 |
|
| notation |
CHEBI:6078 |
|
| prefLabel |
Ivermectin |
|
| smiles |
[H][C@@]12C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)[C@@H](C)C[*])O2)[C@]34O |
|
| textual definition |
A mixture consisting of >= 80% 22,23-dihydroavermectin B1a and <= 20% 22,23-dihydroavermectin B1b. It is a semi-synthetic derivative of abamectin. A broad-spectrum antiparasite medication, particularly against worms (except tapeworms) but also effective againstmost mites and some lice A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice. |
|
| subClassOf |