loading...| Preferred Name |
azithromycin |
|
| Synonyms |
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one azitromicina CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O azithromycinum C38H72N2O12 InChIKey=MQTOSJVFKKJCRP-BICOPXKESA-N azithromycine Azenil Azifast Azigram Azimakrol Azitromin Hemomycin Zithromax Zmax |
|
| Definitions |
A macrolide antibiotic useful for the treatment of bacterial infections. A macrolide antibiotic that has formula C38H72N2O12. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2955 |
|
| charge |
0 |
|
| chemical inhibits in vitro replication of virus | ||
| chemical inhibits protein | ||
| database_cross_reference |
Patent:US4517359 KEGG COMPOUND:C06838 KEGG:C06838 KEGG:D07486 Patent:BE892357 KEGG DRUG:D07486 PDBeChem:ZIT HMDB:HMDB0014352 Drug_Central:276 ChemIDplus:83905-01-5 LINCS:LSM-5821 Reaxys:8820027 Wikipedia:Azithromycin CAS:83905-01-5 PMID:15143799 Reaxys:5387583 DrugBank:DB00207 PMID:18253999 Beilstein:5387583 |
|
| definition source |
PMID: 32533455 https://www.drugbank.ca/drugs/DB00207 Reference: PMID: 24794904 |
|
| formula |
C38H72N2O12 |
|
| has exact synonym |
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35703 |
|
| has_alternative_id |
CHEBI:46596 |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one azitromicina CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O azithromycinum C38H72N2O12 InChIKey=MQTOSJVFKKJCRP-BICOPXKESA-N azithromycine Azenil Azifast Azigram Azimakrol Azitromin Hemomycin Zithromax Zmax |
|
| has_role | ||
| has_RxCUI |
18631 |
|
| id |
CHEBI:2955 |
|
| imported from | ||
| in subset | ||
| inchi |
InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
|
| inchikey |
MQTOSJVFKKJCRP-BICOPXKESA-N |
|
| label |
Azithromycin azithromycin |
|
| mass |
748.98450 |
|
| monoisotopicmass |
748.50853 |
|
| notation |
CHEBI:2955 |
|
| prefLabel |
azithromycin |
|
| smiles |
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O |
|
| textual definition |
A macrolide antibiotic useful for the treatment of bacterial infections. A macrolide antibiotic that has formula C38H72N2O12. |
|
| subClassOf |
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