Link to this page
Chemical Entities of Biological Interest Ontology
Last uploaded:
December 1, 2024
Jump to:
| Preferred Name | trichlormethiazide | |
| Synonyms |
hydrotrichlorothiazide trichlormethiazide triclormetiazida trichlormethiazidum 6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
|
| Definitions |
A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9683 |
|
| charge |
0
|
|
| database_cross_reference |
Wikipedia:Trichlormethiazide PMID:25938807 KEGG:C07767 PMID:28166217 CAS:133-67-5 Drug_Central:2733 LINCS:LSM-4383 PMID:28089902 PMID:25692026 DrugBank:DB01021 PMID:24678944 PMID:21605415 KEGG:D00658 PMID:29438107
|
|
| definition |
A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.
|
|
| formula |
C8H8Cl3N3O4S2
|
|
| has role | ||
| has_exact_synonym |
6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
hydrotrichlorothiazide trichlormethiazide triclormetiazida trichlormethiazidum
|
|
| id |
CHEBI:9683
|
|
| in_subset | ||
| inchi |
InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
|
|
| inchikey |
LMJSLTNSBFUCMU-UHFFFAOYSA-N
|
|
| label |
trichlormethiazide
|
|
| mass |
380.658
|
|
| monoisotopicmass |
378.90218
|
|
| notation |
CHEBI:9683
|
|
| prefLabel |
trichlormethiazide
|
|
| smiles |
C12=C(NC(C(Cl)Cl)NS1(=O)=O)C=C(Cl)C(=C2)S(N)(=O)=O
|
|
| treeView | ||
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping