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Chemical Entities of Biological Interest Ontology
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January 1, 2025
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Id | http://purl.obolibrary.org/obo/CHEBI_75393
http://purl.obolibrary.org/obo/CHEBI_75393
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Preferred Name | Y-27632 |
Definitions |
A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme.
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Synonyms |
4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide
(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
Y 27632
trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme. |
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label | Y-27632
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prefLabel | Y-27632
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database_cross_reference |
Reaxys:9134889
PMID:17157292
DrugBank:DB08756
Wikipedia:Y-27632
CAS:146986-50-7
PMID:10686302
PMID:10973620
PMID:17428993
PMID:17105828
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notation | CHEBI:75393
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in_subset | |
inchi | InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1
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has_related_synonym |
4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide
(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
Y 27632
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id | CHEBI:75393
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charge | 0
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has_obo_namespace | chebi_ontology
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formula | C14H21N3O
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subClassOf | |
inchikey | IYOZTVGMEWJPKR-IJLUTSLNSA-N
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mass | 247.33600
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monoisotopicmass | 247.16846
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type | |
smiles | C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1
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has role | |
has_exact_synonym | trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide
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Subject | Author | Type | Class | Created |
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Need GABA antagonist | bandrow | Comment | http://purl.obolibrary.org/obo/CHEBI_35499 | 2010-10-28 |
Spelling error | memartone | Comment | http://purl.obolibrary.org/obo/CHEBI_15355 | 2010-08-04 |
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