Chemical Entities of Biological Interest Ontology

Last uploaded: December 1, 2024
Jump to:
Preferred Name

pitavastatin calcium
Synonyms

Pitavastatin hemicalcium

Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate) monocalcium salt

calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate}
Definitions

The calcium salt of pitavastatin. Used for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.
ID

http://purl.obolibrary.org/obo/CHEBI_71258
charge

0
database_cross_reference

PMID:21381428

Patent:US2009182008

Patent:KR20110092804

Wikipedia:Pitavastatin

Patent:WO2012025939

Patent:WO2007132482

PMID:21651447

Patent:WO2011105649

Patent:WO2007125547

PMID:21225019

Patent:WO2005063711

PMID:21069103

KEGG:D01862

Patent:US2011319624

PMID:21816477

PMID:20852754

Patent:KR20110097058

CAS:147526-32-7

PMID:20664824

Patent:US2011082298

Patent:US2012016129

Patent:EP2383260

Patent:WO2012002741

Reaxys:7965530

PMID:20621877

Patent:US2012101126
definition

The calcium salt of pitavastatin. Used for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.
formula

C50H46CaF2N2O8
has part

http://purl.obolibrary.org/obo/CHEBI_71260
has role

http://purl.obolibrary.org/obo/CHEBI_22586
has_exact_synonym

calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate}
has_obo_namespace

chebi_ontology
has_related_synonym

Pitavastatin hemicalcium

Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate) monocalcium salt
id

CHEBI:71258
in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR
inchi

InChI=1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
inchikey

RHGYHLPFVJEAOC-FFNUKLMVSA-L
label

pitavastatin calcium
mass

880.98400
monoisotopicmass

880.28481
notation

CHEBI:71258
prefLabel

pitavastatin calcium
smiles

[Ca++].O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O.O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O
treeView

http://purl.obolibrary.org/obo/CHEBI_35156

http://purl.obolibrary.org/obo/CHEBI_87635
subClassOf

http://purl.obolibrary.org/obo/CHEBI_35156

http://purl.obolibrary.org/obo/CHEBI_87635
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display