loading...| Preferred Name |
carglumic acid |
|
| Synonyms |
N-carbamoyl-L-glutamic acid Carbamylglutamic acid acido carglumico L-N-Carbamoylglutamic acid (2S)-2-(carbamoylamino)pentanedioic acid Ureidoglutaric acid acide carglumique Carbamino-L-glutamic acid acidum carglumicum Carbaglu carglumic acid |
|
| Definitions |
A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_71028 |
|
| charge |
0 |
|
| database_cross_reference |
Reaxys:1727929 PMID:18604903 CAS:1188-38-1 PMID:21225012 HMDB:HMDB0015673 PMID:15055204 KEGG:D07130 PMID:22858088 Wikipedia:Carglumic_acid KEGG:C05829 Drug_Central:3068 DrugBank:DB06775 PMID:21941437 PMID:18516804 PMID:17421020 PMID:20410539 PMID:18234091 PMID:21403788 MetaCyc:N-CARBAMYL-L-GLUTAMATE PMID:21207059 |
|
| definition |
A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. |
|
| formula |
C6H10N2O5 |
|
| has role | ||
| has_exact_synonym |
N-carbamoyl-L-glutamic acid |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
Carbamylglutamic acid acido carglumico L-N-Carbamoylglutamic acid (2S)-2-(carbamoylamino)pentanedioic acid Ureidoglutaric acid acide carglumique Carbamino-L-glutamic acid acidum carglumicum Carbaglu carglumic acid |
|
| id |
CHEBI:71028 |
|
| in_subset | ||
| inchi |
InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1 |
|
| inchikey |
LCQLHJZYVOQKHU-VKHMYHEASA-N |
|
| is conjugate acid of | ||
| label |
carglumic acid |
|
| mass |
190.15400 |
|
| monoisotopicmass |
190.05897 |
|
| notation |
CHEBI:71028 |
|
| prefLabel |
carglumic acid |
|
| smiles |
NC(=O)N[C@@H](CCC(O)=O)C(O)=O |
|
| treeView | ||
| subClassOf |