loading...| Preferred Name |
desoximetasone |
|
| Synonyms |
desoximetasona desoximetasonum desoximetasone desoxymethasone 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione 9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione |
|
| Definitions |
Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_691037 |
|
| charge |
0 |
|
| database_cross_reference |
Patent:US3232839 KEGG:D03697 DrugBank:DB00547 CAS:382-67-2 Drug_Central:819 Beilstein:2228097 Patent:FR1296544 Wikipedia:Desoximetasone Patent:US3099654 Patent:BE314196 |
|
| definition |
Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis. |
|
| formula |
C22H29FO4 |
|
| has role | ||
| has_exact_synonym |
9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
desoximetasona desoximetasonum desoximetasone desoxymethasone 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione |
|
| id |
CHEBI:691037 |
|
| in_subset | ||
| inchi |
InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1 |
|
| inchikey |
VWVSBHGCDBMOOT-IIEHVVJPSA-N |
|
| label |
desoximetasone |
|
| mass |
376.46170 |
|
| monoisotopicmass |
376.20499 |
|
| notation |
CHEBI:691037 |
|
| prefLabel |
desoximetasone |
|
| smiles |
[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_139590 http://purl.obolibrary.org/obo/CHEBI_36885 http://purl.obolibrary.org/obo/CHEBI_24261 http://purl.obolibrary.org/obo/CHEBI_77166 http://purl.obolibrary.org/obo/CHEBI_50830 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_139590 http://purl.obolibrary.org/obo/CHEBI_36885 http://purl.obolibrary.org/obo/CHEBI_24261 http://purl.obolibrary.org/obo/CHEBI_77166 http://purl.obolibrary.org/obo/CHEBI_50830 |