loading...| Preferred Name |
megestrol acetate |
|
| Synonyms |
6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate SC-10363 Megace 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate BDH-1298 Megestil Megeron magestin Pallace 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate 6-dehydro-6-methyl-17alpha-acetoxyprogesterone SC 10363 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione BDH 1298 Megestin 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate Ovarid 6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-methyl-6-dehydro-17alpha-acetoxyprogesterone 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione SC10363 Ovaban 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone Megestat Maygace Volidan 17alpha-acetoxy-6-dehydro-6-methylprogesterone Niagestin BDH1298 |
|
| Definitions |
A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6723 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:27218795 KEGG:D00952 PMID:27639080 PMID:11986264 PMID:31451262 PMID:31359357 PMID:29542279 Patent:GB870286 Patent:US2891079 Wikipedia:Megestrol_acetate PMCID:PMC7207385 PMID:28986550 PMID:29442239 Beilstein:1917291 PMID:31497435 DrugBank:DB00351 PMID:30112227 Patent:US3400137 PMID:32084501 PMID:30157059 CAS:595-33-5 PMID:31036192 PMID:32122805 PMID:31462353 KEGG:C08151 PMID:29095656 PMID:29581752 PMID:5320316 PMID:29050522 PMID:31961463 PMID:32652300 PMID:27038209 LIPID_MAPS_instance:LMST02030118 PMID:29400904 Patent:US3356573 |
|
| definition |
A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. |
|
| formula |
C24H32O4 |
|
| has functional parent | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_50779 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_59826 |
|
| has_exact_synonym |
6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
SC-10363 Megace 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate BDH-1298 Megestil Megeron magestin Pallace 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate 6-dehydro-6-methyl-17alpha-acetoxyprogesterone SC 10363 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione BDH 1298 Megestin 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate Ovarid 6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-methyl-6-dehydro-17alpha-acetoxyprogesterone 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione SC10363 Ovaban 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone Megestat Maygace Volidan 17alpha-acetoxy-6-dehydro-6-methylprogesterone Niagestin BDH1298 |
|
| id |
CHEBI:6723 |
|
| in_subset | ||
| inchi |
InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1 |
|
| inchikey |
RQZAXGRLVPAYTJ-GQFGMJRRSA-N |
|
| label |
megestrol acetate |
|
| mass |
370.48190 |
|
| monoisotopicmass |
370.21441 |
|
| notation |
CHEBI:6723 |
|
| prefLabel |
megestrol acetate |
|
| smiles |
[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_47880 http://purl.obolibrary.org/obo/CHEBI_47622 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_47880 http://purl.obolibrary.org/obo/CHEBI_47622 |