Chemical Entities of Biological Interest Ontology

Last uploaded: November 5, 2024
Jump to:
loading...
Preferred Name

levobunolol
Synonyms

(-)-Bunolol

levobunololum

(S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone

5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one

Levobunolol
Definitions

A cyclic ketone that is 3,4-dihydronaphthalen-1-one substituted at position 5 by a 3-(tert-butylamino)-2-hydroxypropoxy group (the S-enantiomer). A non-selective beta-adrenergic antagonist used (as its hydrochloride salt) for treatment of glaucoma.
ID

http://purl.obolibrary.org/obo/CHEBI_6438
charge

0
database_cross_reference

PMID:3067745

PMID:3062528

PMID:2873545

CAS:47141-42-4

PMID:19626454

LINCS:LSM-6578

Wikipedia:Levobunolol

HMDB:HMDB0015341

Patent:WO2011140194

KEGG:D08115

PMID:21368570

PMID:30000211

Patent:US2011275617

PMID:17459374

PMID:37861808

PMID:3019819

DrugBank:DB01210

PMID:3050679

PMID:26227808

Drug_Central:431

Patent:WO2008002929

PMID:29277497

PMID:27190057

Reaxys:6484587

PMID:3513594

KEGG:C07914

PMID:3881032

PMID:20960417

PMID:3912600

PMID:2881799

Patent:US2011263638

PMID:34863129

PMID:3058836

PMID:23390358
definition

A cyclic ketone that is 3,4-dihydronaphthalen-1-one substituted at position 5 by a 3-(tert-butylamino)-2-hydroxypropoxy group (the S-enantiomer). A non-selective beta-adrenergic antagonist used (as its hydrochloride salt) for treatment of glaucoma.
formula

C17H25NO3
has parent hydride

http://purl.obolibrary.org/obo/CHEBI_35008
has role

http://purl.obolibrary.org/obo/CHEBI_39456

http://purl.obolibrary.org/obo/CHEBI_35530
has_exact_synonym

5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one

Levobunolol
has_obo_namespace

chebi_ontology
has_related_synonym

(-)-Bunolol

levobunololum

(S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone
id

CHEBI:6438
in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR
inchi

InChI=1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1
inchikey

IXHBTMCLRNMKHZ-LBPRGKRZSA-N
is conjugate base of

http://purl.obolibrary.org/obo/CHEBI_72567
label

levobunolol
mass

291.38534
monoisotopicmass

291.18344
notation

CHEBI:6438
prefLabel

levobunolol
smiles

CC(C)(C)NC[C@H](O)COc1cccc2C(=O)CCCc12
treeView

http://purl.obolibrary.org/obo/CHEBI_35533

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_3992
subClassOf

http://purl.obolibrary.org/obo/CHEBI_35533

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_3992
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_6438 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6438 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6438 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6438 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6438 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6438 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6438 NIFSTD SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62043 NCIT LOOM
http://purl.bioontology.org/ontology/RCD/x01C8 RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2224 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C62043 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.638.960.446.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.638.960.446.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147888 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D002040 MESH LOOM
http://purl.bioontology.org/ontology/ATC/S01ED03 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/1813 RXNORM LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00569 OCIMIDO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.100.624.698.115.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0006388 OCHV LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015696 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6438 NIFSTD LOOM
https://go.drugbank.com/drugs/DB01210 MDM LOOM
http://purl.jp/bio/4/id/200906037354162757 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Levobunolol GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002040 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.063.624.698.115.500 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907005441373211 IOBC LOOM
http://purl.obolibrary.org/obo/MESH_D002040 BERO LOOM
http://purl.bioontology.org/ontology/VANDF/4019799 VANDF LOOM
http://www.drugbank.ca/drugs/DB01210 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.755.624.698.115.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0003390 OMIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/418934007 SNOMEDCT LOOM