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Chemical Entities of Biological Interest Ontology
| Preferred Name | doxazosin | |
| Synonyms |
doxazosina doxazosinum 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin doxazosin doxazosine Doxazosin 2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine |
|
| Definitions |
A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4708 |
|
| charge |
0
|
|
| database_cross_reference |
PMID:17171413 Drug_Central:954 DrugBank:DB00590 Wikipedia:Doxazosin KEGG:C06970 Patent:US4188390 Reaxys:731849 KEGG:D07874 PMID:18559700 HMDB:HMDB0014728 CAS:74191-85-8 Patent:DE2847623 LINCS:LSM-4335
|
|
| definition |
A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
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|
| formula |
C23H25N5O5
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|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_37890 |
|
| has_exact_synonym |
Doxazosin 2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
doxazosina doxazosinum 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin doxazosin doxazosine
|
|
| id |
CHEBI:4708
|
|
| in_subset | ||
| inchi |
InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)
|
|
| inchikey |
RUZYUOTYCVRMRZ-UHFFFAOYSA-N
|
|
| label |
doxazosin
|
|
| mass |
451.47510
|
|
| monoisotopicmass |
451.18557
|
|
| notation |
CHEBI:4708
|
|
| prefLabel |
doxazosin
|
|
| smiles |
COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1COc2ccccc2O1
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|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_46844 http://purl.obolibrary.org/obo/CHEBI_33860 http://purl.obolibrary.org/obo/CHEBI_38530 http://purl.obolibrary.org/obo/CHEBI_46848 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_46844 http://purl.obolibrary.org/obo/CHEBI_33860 http://purl.obolibrary.org/obo/CHEBI_38530 http://purl.obolibrary.org/obo/CHEBI_46848 |
| Delete | Subject | Author | Type | Created |
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