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Chemical Entities of Biological Interest Ontology
| Preferred Name | dapsone | |
| Synonyms |
4-aminophenyl sulfone p,p-sulphonylbisbenzamine bis(4-aminophenyl)sulfone 4,4'-Sulfonylbisbenzenamine Bis(p-aminophenyl) sulfone p,p-sulphonylbisbenzenamine dapsone 4,4'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)aniline DIAPHENYLSULFONE p,p'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)benzenamine dapsonum DADPS 4-(4-amino-benzenesulfonyl)-phenylamine dapsona DDS 4,4'-sulfonylbisaniline 1,1'-sulfonylbis(4-aminobenzene) p-aminophenyl sulfone Diaphenylsulfone 4,4'-dapsone DAPSONE Dapsone 4,4'-sulfonyldianiline |
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| Definitions |
A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4325 |
|
| charge |
0
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| database_cross_reference |
Patent:FR829926 PMID:28434260 LINCS:LSM-5714 PMID:28732451 KEGG:D00592 KEGG:C07666 PMID:29045131 PMID:18035772 Wikipedia:Dapsone Drug_Central:782 PMID:24232126 PMID:16361748 PMID:28699887 PMID:29280553 PMID:29192974 PMID:29233746 CAS:80-08-0 Reaxys:788055 PMID:24512442 HMDB:HMDB0014395 PMID:29192999 DrugBank:DB00250
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|
| definition |
A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.
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| formula |
C12H12N2O2S
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| has functional parent | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35441 http://purl.obolibrary.org/obo/CHEBI_35472 |
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| has_alternative_id |
CHEBI:226356
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|
| has_exact_synonym |
DAPSONE Dapsone 4,4'-sulfonyldianiline
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| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
4-aminophenyl sulfone p,p-sulphonylbisbenzamine bis(4-aminophenyl)sulfone 4,4'-Sulfonylbisbenzenamine Bis(p-aminophenyl) sulfone p,p-sulphonylbisbenzenamine dapsone 4,4'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)aniline DIAPHENYLSULFONE p,p'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)benzenamine dapsonum DADPS 4-(4-amino-benzenesulfonyl)-phenylamine dapsona DDS 4,4'-sulfonylbisaniline 1,1'-sulfonylbis(4-aminobenzene) p-aminophenyl sulfone Diaphenylsulfone 4,4'-dapsone
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|
| id |
CHEBI:4325
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| in_subset | ||
| inchi |
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
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|
| inchikey |
MQJKPEGWNLWLTK-UHFFFAOYSA-N
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|
| label |
dapsone
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|
| mass |
248.30100
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|
| monoisotopicmass |
248.06195
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|
| notation |
CHEBI:4325
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|
| prefLabel |
dapsone
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|
| smiles |
Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
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| treeView | ||
| subClassOf |
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