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Chemical Entities of Biological Interest Ontology
| Preferred Name | cyproheptadine | |
| Synonyms |
ciproheptadina cyproheptadinum 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine 5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine cyproheptadine 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine Cyproheptadine 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine CYPROHEPTADINE 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine |
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| Definitions |
The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4046 |
|
| charge |
0
|
|
| database_cross_reference |
Drug_Central:765 CAS:129-03-3 PMID:10843226 LINCS:LSM-5419 Patent:US3014911 KEGG:C06935 Wikipedia:Cyproheptadine Beilstein:1348386 KEGG:D07765 DrugBank:DB00434
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|
| definition |
The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
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|
| formula |
C21H21N
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|
| has role |
http://purl.obolibrary.org/obo/CHEBI_37955 http://purl.obolibrary.org/obo/CHEBI_55324 http://purl.obolibrary.org/obo/CHEBI_48279 |
|
| has_alternative_id |
CHEBI:111005 CHEBI:605605
|
|
| has_exact_synonym |
Cyproheptadine 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine CYPROHEPTADINE 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine cyproheptadine
|
|
| has_obo_namespace |
chebi_ontology
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|
| has_related_synonym |
ciproheptadina cyproheptadinum 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine 5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine cyproheptadine 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
|
|
| id |
CHEBI:4046
|
|
| in_subset | ||
| inchi |
InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
|
|
| inchikey |
JJCFRYNCJDLXIK-UHFFFAOYSA-N
|
|
| label |
cyproheptadine
|
|
| mass |
287.39810
|
|
| monoisotopicmass |
287.16740
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|
| notation |
CHEBI:4046
|
|
| prefLabel |
cyproheptadine
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|
| smiles |
CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
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| treeView | ||
| subClassOf |
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