loading...| Preferred Name | fluvastatin | |
| Synonyms |
fluvastatinum rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid fluvastatina (+-)-fluvastatin fluvastatine erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid fluvastatin (6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid rac-(3R,5S)-fluvastatin Cranoc rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid |
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| Definitions |
A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_38561 |
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| charge |
0 |
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| database_cross_reference |
KEGG:D07983 Beilstein:9168031 PMID:18936176 DrugBank:DB01095 PMID:23846727 Patent:WO8402131 CAS:93957-54-1 PMID:11273020 KEGG:C07014 Wikipedia:Fluvastatin PMID:18413661 PMID:12147804 PMID:23212095 PMID:18452779 Patent:US4739073 PMID:18410471 |
|
| definition |
A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia. |
|
| formula |
C24H26FNO4 |
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| has part | ||
| has role | ||
| has_exact_synonym |
rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid |
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| has_obo_namespace |
chebi_ontology |
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| has_related_synonym |
fluvastatinum rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid fluvastatina (+-)-fluvastatin fluvastatine erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid fluvastatin (6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid rac-(3R,5S)-fluvastatin Cranoc |
|
| id |
CHEBI:38561 |
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| in_subset | ||
| inchi |
InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m0/s1 |
|
| inchikey |
FJLGEFLZQAZZCD-JUFISIKESA-N |
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| label |
fluvastatin |
|
| mass |
411.467 |
|
| monoisotopicmass |
411.18459 |
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| notation |
CHEBI:38561 |
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| prefLabel |
fluvastatin |
|
| smiles |
C1(=CC=C(C=C1)C=2C=3C(N(C2/C=C/[C@@H](C[C@@H](CC(O)=O)O)O)C(C)C)=CC=CC3)F |
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| treeView | ||
| subClassOf |