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Chemical Entities of Biological Interest Ontology
Last uploaded:
December 1, 2024
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| Preferred Name | betahistine | |
| Synonyms |
2-(beta-methylaminoethyl)pyridine betahistine 2-[2-(methylamino)ethyl]pyridine N-methyl-2-pyridineethanamine betahistinum betahistina N-methyl-2-(2-pyridinyl)ethanamine [2-(2-pyridyl)ethyl]methylamine N-methyl-2-pyridin-2-ylethanamine |
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| Definitions |
An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_35677 |
|
| charge |
0
|
|
| database_cross_reference |
PMID:20530654 PMID:22745706 Wikipedia:Betahistine PMID:22365373 LINCS:LSM-4044 Reaxys:112294 PMID:7589314 Drug_Central:346 KEGG:D07522 CAS:5638-76-6 HMDB:HMDB0015644 DrugBank:DB06698
|
|
| definition |
An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.
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|
| formula |
C8H12N2
|
|
| has role | ||
| has_exact_synonym |
N-methyl-2-pyridin-2-ylethanamine
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|
| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
2-(beta-methylaminoethyl)pyridine betahistine 2-[2-(methylamino)ethyl]pyridine N-methyl-2-pyridineethanamine betahistinum betahistina N-methyl-2-(2-pyridinyl)ethanamine [2-(2-pyridyl)ethyl]methylamine
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|
| id |
CHEBI:35677
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|
| in_subset | ||
| inchi |
InChI=1S/C8H12N2/c1-9-7-5-8-4-2-3-6-10-8/h2-4,6,9H,5,7H2,1H3
|
|
| inchikey |
UUQMNUMQCIQDMZ-UHFFFAOYSA-N
|
|
| label |
betahistine
|
|
| mass |
136.19430
|
|
| monoisotopicmass |
136.10005
|
|
| notation |
CHEBI:35677
|
|
| prefLabel |
betahistine
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|
| smiles |
CNCCc1ccccn1
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| treeView | ||
| subClassOf |
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