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Chemical Entities of Biological Interest Ontology
Last uploaded:
December 1, 2024
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| Preferred Name | droxidopa | |
| Synonyms |
L-DOPS (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid droxidopum Droxydopa SM 5688 threo-Dopaserine Northera L-Threodops L-Dihydroxyphenylserine (2S,3R)-3,4-dihydroxy-phenylserine L-threo-dihydroxyphenylserine droxidopa Dops (betaR)-beta,3-dihydroxy-L-tyrosine |
|
| Definitions |
A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_31524 |
|
| charge |
0
|
|
| database_cross_reference |
Reaxys:7112431 PMID:23224983 PMID:20063034 Patent:JP2005247828 Drug_Central:971 PMID:24517276 PMID:24729712 KEGG:D01277 Patent:US2012010293 PMID:20207766 PMID:24326693 CAS:23651-95-8 PMID:20220040 PMID:24944260 DrugBank:DB06262 PMID:24224390 PMID:22610782 Patent:US2008221170 PMID:11710796 PMID:24958960 PMID:21705113 HMDB:HMDB0015627 PMID:24644107 PMID:22561478 Patent:NZ579368 Patent:US2013253061 PMID:24883005 Wikipedia:Droxidopa
|
|
| definition |
A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension
|
|
| formula |
C9H11NO5
|
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35674 |
|
| has_exact_synonym |
(betaR)-beta,3-dihydroxy-L-tyrosine
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|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
L-DOPS (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid droxidopum Droxydopa SM 5688 threo-Dopaserine Northera L-Threodops L-Dihydroxyphenylserine (2S,3R)-3,4-dihydroxy-phenylserine L-threo-dihydroxyphenylserine droxidopa Dops
|
|
| id |
CHEBI:31524
|
|
| in_subset | ||
| inchi |
InChI=1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1
|
|
| inchikey |
QXWYKJLNLSIPIN-JGVFFNPUSA-N
|
|
| label |
droxidopa
|
|
| mass |
213.18730
|
|
| monoisotopicmass |
213.06372
|
|
| notation |
CHEBI:31524
|
|
| prefLabel |
droxidopa
|
|
| smiles |
N[C@@H]([C@H](O)c1ccc(O)c(O)c1)C(O)=O
|
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| treeView | ||
| subClassOf |
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