loading...| Preferred Name |
lumefantrine |
|
| Synonyms |
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol Lumefantrine 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol (+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol dl-Benflumelol Benflumetol |
|
| Definitions |
A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_156095 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:12565929 PMID:12798326 Wikipedia:Lumefantrine KEGG:D03821 Beilstein:8811003 CAS:82186-77-4 DrugBank:DB06708 Drug_Central:1617 PMID:12699750 |
|
| definition |
A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria. |
|
| formula |
C30H32Cl3NO |
|
| has role | ||
| has_exact_synonym |
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol Lumefantrine 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol (+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol dl-Benflumelol Benflumetol |
|
| id |
CHEBI:156095 |
|
| in_subset | ||
| inchi |
InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15- |
|
| inchikey |
DYLGFOYVTXJFJP-MYYYXRDXSA-N |
|
| label |
lumefantrine |
|
| mass |
528.94000 |
|
| monoisotopicmass |
527.15495 |
|
| notation |
CHEBI:156095 |
|
| prefLabel |
lumefantrine |
|
| smiles |
CCCCN(CCCC)CC(O)c1cc(Cl)cc2\C(=C/c3ccc(Cl)cc3)c3cc(Cl)ccc3-c12 |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_32876 http://purl.obolibrary.org/obo/CHEBI_83403 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_32876 http://purl.obolibrary.org/obo/CHEBI_83403 |