Preferred Name |
Stevens-Johnson syndrome |
|
Synonyms |
Erythema multiforme major Stevens johnson syndrome |
|
Definitions |
A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis. The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces. The lesions are vesicular or necrotic in the center, surrounded by an erythematous zone and occupy less than 10% of the body surfaces. The appearance of the mucocutaneous lesions is preceded by an upper respiratory tract infection. It is an immune complex hypersensitivity reaction usually caused by drugs (e.g., sulfa, phenytoin, penicillin), viruses (e.g., herpes simplex, influenza, hepatitis), and malignancies (e.g., carcinoma and lymphoma) OR A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. |
|
ID |
http://purl.obolibrary.org/obo/CCTO_001081 |
|
database_cross_reference |
UMLS:C3241919 UMLS:C0038325 NCIT:C79484 NCI:CTCAE:10042033 |
|
definition |
A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis. The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces. The lesions are vesicular or necrotic in the center, surrounded by an erythematous zone and occupy less than 10% of the body surfaces. The appearance of the mucocutaneous lesions is preceded by an upper respiratory tract infection. It is an immune complex hypersensitivity reaction usually caused by drugs (e.g., sulfa, phenytoin, penicillin), viruses (e.g., herpes simplex, influenza, hepatitis), and malignancies (e.g., carcinoma and lymphoma) OR A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. |
|
has_exact_synonym |
Erythema multiforme major Stevens johnson syndrome |
|
has_obo_namespace |
cancer_care_treatment_outcome |
|
id |
CCTO:001081 |
|
label |
Stevens-Johnson syndrome |
|
notation |
CCTO:001081 |
|
prefLabel |
Stevens-Johnson syndrome |
|
schema |
CCTO:001081(time_t t0) = EVENT_STATE(CCTO:001081, t0) |
|
treeView | ||
XSTOO_rule |
CCTO:001081 implies CCTO:000049 CCTO:001081 implies CCTO:001128 |
|
subClassOf | ||
is_assessed_by |