loading...| Preferred Name | salmeterol | |
| Synonyms |
(+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol (+-)-salmeterol (RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol (RS)-salmeterol salmeterolum salmeterol Salmeterol |
|
| Definitions |
A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9011 |
|
| charge |
0 |
|
| database_cross_reference |
KEGG:C07241 NCIt:C29443 CiteXplore:22192967 CiteXplore:22245487 PMID:22192967 MeSH:C057823 KEGG:D05792 SNOMEDCT:372515005 Wikipedia:Salmeterol CiteXplore:22231554 KEGG COMPOUND:C07241 SNOMEDCT:108605008 ChemIDplus:89365-50-4 PMID:22235841 PMID:22231554 CiteXplore:22235841 DrugBank:DB00938 PMID:22245487 HMDB:HMDB0015073 Patent:DE3414752 KEGG COMPOUND:89365-50-4 CAS:89365-50-4 KEGG DRUG:D05792 Patent:US4992474 |
|
| definition |
A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation. |
|
| formula |
C25H37NO4 |
|
| has characteristic | ||
| has_exact_synonym |
Salmeterol |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
(+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol (+-)-salmeterol (RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol (RS)-salmeterol salmeterolum salmeterol |
|
| has_role | ||
| id |
CHEBI:9011 |
|
| in_subset | ||
| label |
salmeterol |
|
| mass |
415.56560 |
|
| monoisotopicmass |
415.27226 |
|
| notation |
CHEBI:9011 |
|
| preferred label |
salmeterol |
|
| prefLabel |
salmeterol |
|
| subClassOf |