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Cell Culture Ontology
| Preferred Name | felodipine | |
| Synonyms |
felodipinum 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (+-)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester felodipina felodipine ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate FELODIPINE |
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| Definitions |
The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_585948 |
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| charge |
0
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| database_cross_reference |
Patent:EP7293 PMID:18457386 DrugBank:DB01023 Patent:US4264611 CAS:72509-76-3 PDBeChem:225 Drug_Central:1142 Wikipedia:Felodipine KEGG:D00319 Reaxys:4331472 LINCS:LSM-1447
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| definition |
The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
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| formula |
C18H19Cl2NO4
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| has_alternative_id |
CHEBI:49383 CHEBI:4996
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| has_exact_synonym |
ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate FELODIPINE
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| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
felodipinum 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (+-)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester felodipina felodipine
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|
| id |
CHEBI:585948
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| in_subset | ||
| inchi |
InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
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| inchikey |
RZTAMFZIAATZDJ-UHFFFAOYSA-N
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|
| label |
felodipine
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|
| mass |
384.25400
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|
| monoisotopicmass |
383.06911
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| notation |
CHEBI:585948
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| preferred label |
felodipine
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| prefLabel |
felodipine
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| smiles |
CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(Cl)c1Cl)C(=O)OC
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| subClassOf |
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