Preferred Name |
Plasminogen deficiency |
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Synonyms |
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Definitions |
(PLGD): A disorder characterized by decreased serum plasminogen activity. Two forms of the disorder are distinguished: type 1 deficiency is additionally characterized by decreased plasminogen antigen levels and clinical symptoms, whereas type 2 deficiency, also known as dysplasminogenemia, is characterized by normal, or slightly reduced antigen levels, and absence of clinical manifestations. Plasminogen deficiency type 1 results in markedly impaired extracellular fibrinolysis and chronic mucosal pseudomembranous lesions due to subepithelial fibrin deposition and inflammation. The most common clinical manifestation of type 1 deficiency is ligneous conjunctivitis in which pseudomembranes formation on the palpebral surfaces of the eye progresses to white, yellow-white, or red thick masses with a wood-like consistency that replace the normal mucosa. |
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ID |
http://purl.obolibrary.org/obo/OMIM_217090 |
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definition |
(PLGD): A disorder characterized by decreased serum plasminogen activity. Two forms of the disorder are distinguished: type 1 deficiency is additionally characterized by decreased plasminogen antigen levels and clinical symptoms, whereas type 2 deficiency, also known as dysplasminogenemia, is characterized by normal, or slightly reduced antigen levels, and absence of clinical manifestations. Plasminogen deficiency type 1 results in markedly impaired extracellular fibrinolysis and chronic mucosal pseudomembranous lesions due to subepithelial fibrin deposition and inflammation. The most common clinical manifestation of type 1 deficiency is ligneous conjunctivitis in which pseudomembranes formation on the palpebral surfaces of the eye progresses to white, yellow-white, or red thick masses with a wood-like consistency that replace the normal mucosa. |
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has_obo_namespace |
cell_cycle_ontology |
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id |
OMIM:217090 |
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label |
Plasminogen deficiency |
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notation |
OMIM:217090 |
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prefLabel |
Plasminogen deficiency |
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treeView | ||
subClassOf |
Delete | Mapping To | Ontology | Source |
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http://purl.bioontology.org/ontology/RCD/X20Eh | RCD | LOOM | |
http://identifiers.org/omim/217090 | REXO | LOOM | |
http://identifiers.org/omim/217090 | GEXO | LOOM | |
http://identifiers.org/omim/217090 | RETO | LOOM | |
http://sbmi.uth.tmc.edu/ontology/ochv#C0398621 | OCHV | LOOM | |
http://purl.bioontology.org/ontology/ICD10CM/E88.02 | ICD10CM | LOOM |