BRENDA Tissue and Enzyme Source Ontology

Last uploaded: February 4, 2022
Preferred Name

K7M2-WT cell

Synonyms

K7M2 wt cell

K7M2 cell

Definitions

Murine osteosarcoma cell line; derived by intra-osseous injection of the K7 murine osteosarcoma cell line to the proximal tibia of a BALB/c mouse. The resultant primary tumor spontaneously metastasized to the lungs. A pulmonary metastasis was removed from the lung and then surgically implanted to a paraosteal tibial muscle flap of a naïve mouse. This cycle of implantation of pulmonary metastasis to paraosteal tibial muscle flap sites was repeated, resulting in the K7M2 primary tumor. This tumor was dissociated to a single cell suspension to create the K7M2 wt cell line.

ID

http://purl.obolibrary.org/obo/BTO_0006407

created_by

Marion

creation_date

2020-03-27T09:25:50Z

definition

Murine osteosarcoma cell line; derived by intra-osseous injection of the K7 murine osteosarcoma cell line to the proximal tibia of a BALB/c mouse. The resultant primary tumor spontaneously metastasized to the lungs. A pulmonary metastasis was removed from the lung and then surgically implanted to a paraosteal tibial muscle flap of a naïve mouse. This cycle of implantation of pulmonary metastasis to paraosteal tibial muscle flap sites was repeated, resulting in the K7M2 primary tumor. This tumor was dissociated to a single cell suspension to create the K7M2 wt cell line.

develops_from

http://purl.obolibrary.org/obo/BTO_0006408

has_obo_namespace

BrendaTissueOBO

has_related_synonym

K7M2 wt cell

K7M2 cell

id

BTO:0006407

label

K7M2-WT cell

notation

BTO:0006407

prefLabel

K7M2-WT cell

treeView

http://purl.obolibrary.org/obo/BTO_0006408

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