BRENDA Tissue and Enzyme Source Ontology

Last uploaded: February 4, 2022
Preferred Name

KBv200 cell

Synonyms
Definitions

A multidrug-resistant clone of human oral epidermoid carcinoma KB cells was isolated by stepwise selection on exposure to increasing doses of vincristine. The final clone, KBv200, obtained after ethylmethane sulfonate mutagenesis showed 156-fold higher resistance to vincristine than KB cells. The cells were also cross-resistant to paclitaxel and adriamycin.

ID

http://purl.obolibrary.org/obo/BTO_0005196

created_by

XPMUser

creation_date

2011-09-01T08:51:13Z

definition

A multidrug-resistant clone of human oral epidermoid carcinoma KB cells was isolated by stepwise selection on exposure to increasing doses of vincristine. The final clone, KBv200, obtained after ethylmethane sulfonate mutagenesis showed 156-fold higher resistance to vincristine than KB cells. The cells were also cross-resistant to paclitaxel and adriamycin.

develops_from

http://purl.obolibrary.org/obo/BTO_0000665

has_obo_namespace

BrendaTissueOBO

id

BTO:0005196

label

KBv200 cell

notation

BTO:0005196

prefLabel

KBv200 cell

treeView

http://purl.obolibrary.org/obo/BTO_0000665

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