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BRENDA Tissue and Enzyme Source Ontology
Last uploaded:
February 4, 2022
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| Preferred Name | MLE-12 cell | |
| Synonyms |
MLE 12 cell |
|
| Definitions |
Mouse lung cancer cell line. This line was established in 1992 by Kathryn A. Wikenheiser from pulmonary tumors in a mouse transgenic for the SV40 large T antigen under the control of the promoter region of the human surfactant protein C gene. The cells express the mRNA for large T antigen. Lung surfactant proteins B and C were detected. The cells secrete phospholipids in response to phorbol esters and ATP but not in response to forskolin. |
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| ID |
http://purl.obolibrary.org/obo/BTO_0002268 |
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| created_by |
XPMUser
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|
| creation_date |
2013-02-28T04:36:01Z
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|
| definition |
Mouse lung cancer cell line. This line was established in 1992 by Kathryn A. Wikenheiser from pulmonary tumors in a mouse transgenic for the SV40 large T antigen under the control of the promoter region of the human surfactant protein C gene. The cells express the mRNA for large T antigen. Lung surfactant proteins B and C were detected. The cells secrete phospholipids in response to phorbol esters and ATP but not in response to forskolin.
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| has_obo_namespace |
BrendaTissueOBO
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| has_related_synonym |
MLE 12 cell
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|
| id |
BTO:0002268
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|
| label |
MLE-12 cell
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|
| notation |
BTO:0002268
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|
| prefLabel |
MLE-12 cell
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| treeView | ||
| subClassOf |
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