Preferred Name

post-translational protein modification

Synonyms

PTM

post-translational amino acid modification

posttranslational amino acid modification

posttranslational protein modification

posttranslational modification

post-translational modification

Definitions

This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term. The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.

ID

http://purl.obolibrary.org/obo/BiPOm#post-translational_protein_modification

comment

This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.

closeMatch

http://purl.obolibrary.org/obo/GO_0043687

has output

http://purl.obolibrary.org/obo/BiPOm#protein

hasDbXref

Reactome:REACT_81500

Reactome:REACT_87023

Reactome:REACT_83761

Wikipedia:Posttranslational_modification

Reactome:REACT_83056

Reactome:REACT_31587

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Reactome:REACT_78573

Reactome:REACT_104966

Reactome:REACT_83451

Reactome:REACT_1069

Reactome:REACT_91222

Reactome:REACT_33179

Reactome:REACT_91093

Reactome:REACT_105450

Reactome:REACT_78360

Reactome:REACT_89018

Reactome:REACT_103281

Reactome:REACT_22161

Reactome:REACT_100887

Reactome:REACT_81635

Reactome:REACT_88325

Reactome:REACT_29658

Reactome:REACT_85268

Reactome:REACT_31741

Reactome:REACT_109761

Reactome:REACT_96864

Reactome:REACT_91597

Reactome:REACT_103494

Reactome:REACT_88089

Reactome:REACT_33269

Reactome:REACT_34647

Reactome:REACT_82133

Reactome:REACT_33662

Reactome:REACT_101114

Reactome:REACT_113592

hasExactSynonym

PTM

post-translational amino acid modification

posttranslational amino acid modification

posttranslational protein modification

posttranslational modification

post-translational modification

hasOBONamespace

biological_process

IAO_0000115

The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.

id

GO:0043687

inSubset

http://purl.obolibrary.org/obo/go#gosubset_prok

label

post-translational protein modification

notation

GO:0043687

prefLabel

post-translational protein modification

subClassOf

http://purl.obolibrary.org/obo/BiPOm#Biochemical_Reaction

http://purl.obolibrary.org/obo/BiPOm#protein_modification_process

http://purl.obolibrary.org/obo/BiPOm#cellular_protein_modification_process

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