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Biological interlocked Process Ontology for metabolism
| Preferred Name | post-translational protein modification | |
| Synonyms |
PTM post-translational amino acid modification posttranslational amino acid modification posttranslational protein modification posttranslational modification post-translational modification |
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| Definitions |
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term. |
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| ID |
http://purl.obolibrary.org/obo/BiPOm#post-translational_protein_modification |
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| comment |
This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
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| hasDbXref |
Reactome:REACT_81500 Reactome:REACT_87023 Reactome:REACT_83761 Wikipedia:Posttranslational_modification Reactome:REACT_83056 Reactome:REACT_31587 Reactome:REACT_82385 Reactome:REACT_78573 Reactome:REACT_104966 Reactome:REACT_83451 Reactome:REACT_1069 Reactome:REACT_91222 Reactome:REACT_33179 Reactome:REACT_91093 Reactome:REACT_105450 Reactome:REACT_78360 Reactome:REACT_89018 Reactome:REACT_103281 Reactome:REACT_22161 Reactome:REACT_100887 Reactome:REACT_81635 Reactome:REACT_88325 Reactome:REACT_29658 Reactome:REACT_85268 Reactome:REACT_31741 Reactome:REACT_109761 Reactome:REACT_96864 Reactome:REACT_91597 Reactome:REACT_103494 Reactome:REACT_88089 Reactome:REACT_33269 Reactome:REACT_34647 Reactome:REACT_82133 Reactome:REACT_33662 Reactome:REACT_101114 Reactome:REACT_113592
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| hasExactSynonym |
PTM post-translational amino acid modification posttranslational amino acid modification posttranslational protein modification posttranslational modification post-translational modification
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| hasOBONamespace |
biological_process
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| IAO_0000115 |
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
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| id |
GO:0043687
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| inSubset | ||
| label |
post-translational protein modification
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| notation |
GO:0043687
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| prefLabel |
post-translational protein modification
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| subClassOf |
http://purl.obolibrary.org/obo/BiPOm#Biochemical_Reaction http://purl.obolibrary.org/obo/BiPOm#protein_modification_process http://purl.obolibrary.org/obo/BiPOm#cellular_protein_modification_process |
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