loading...| Preferred Name |
doxapram |
|
| Synonyms |
|
|
| Definitions |
N-Ethylpyrrolidin-2-one in which both or the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_681848 |
|
| alternative term |
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3 Doxapram CCN1CC(CCN2CCOCC2)C(C1=O)(c1ccccc1)c1ccccc1 InChIKey=XFDJYSQDBULQSI-UHFFFAOYSA-N C24H30N2O2 doxapram 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone (+-)-doxapram |
|
| definition |
N-Ethylpyrrolidin-2-one in which both or the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering. |
|
| has role | ||
| label |
doxapram |
|
| prefixIRI |
CHEBI:681848 |
|
| prefLabel |
doxapram |
|
| subClassOf |