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BioModels Ontology
Last uploaded:
April 3, 2012
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| Preferred Name | diphenoxylate hydrochloride | |
| Synonyms |
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| Definitions |
The hydrochloride salt of diphenoxylate. A synthetic derivative of meperidine with little or no analgesic activity, it reduces intestinal motility and is used in the symptomatic treatment of acute and chronic diarrhoea; its active metabolite is the corresponding carboxylic acid, difenoxin. In an attempt to discourage abuse (at high doses, diphenoxylate acts like morphine), preparations usually contain subclinical amounts of atropine sulfate. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_59784 |
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| alternative term |
1-(3-cyano-3,3-diphenylpropyl)-4-(ethoxycarbonyl)-4-phenylpiperidinium chloride ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride diphenoxylate HCl C30H33ClN2O2 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid ethyl ester hydrochloride InChIKey=SHTAFWKOISOCBI-UHFFFAOYSA-N InChI=1S/C30H32N2O2.ClH/c1-2-34-28(33)29(25-12-6-3-7-13-25)18-21-32(22-19-29)23-20-30(24-31,26-14-8-4-9-15-26)27-16-10-5-11-17-27;/h3-17H,2,18-23H2,1H3;1H ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride [Cl-].CCOC(=O)C1(CC[NH+](CC1)CCC(C#N)(c1ccccc1)c1ccccc1)c1ccccc1 4-ethoxycarbonyl-alpha,alpha,4-triphenyl-1-piperidinebutyronitrile hydrochloride
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| definition |
The hydrochloride salt of diphenoxylate. A synthetic derivative of meperidine with little or no analgesic activity, it reduces intestinal motility and is used in the symptomatic treatment of acute and chronic diarrhoea; its active metabolite is the corresponding carboxylic acid, difenoxin. In an attempt to discourage abuse (at high doses, diphenoxylate acts like morphine), preparations usually contain subclinical amounts of atropine sulfate.
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| has part | ||
| has role | ||
| label |
diphenoxylate hydrochloride
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| prefixIRI |
CHEBI:59784
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| prefLabel |
diphenoxylate hydrochloride
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| subClassOf |
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