loading...| Preferred Name |
encainide |
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| Synonyms |
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| Definitions |
4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_4788 |
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| alternative term |
encainidum InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25) 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide (+-)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide InChIKey=PJWPNDMDCLXCOM-UHFFFAOYSA-N 4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide encainida 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide Encainide C22H28N2O2 COc1ccc(cc1)C(=O)Nc1ccccc1CCC1CCCCN1C encainide (+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide |
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| definition |
4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market. |
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| has role | ||
| label |
encainide |
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| prefixIRI |
CHEBI:4788 |
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| prefLabel |
encainide |
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| subClassOf |