loading...| Preferred Name |
edrophonium chloride |
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| Synonyms |
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| Definitions |
The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_4759 |
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| alternative term |
InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H edrophonii chloridum 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride EDROPHONIUM CHLORIDE N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride ethyl(m-hydroxyphenyl)dimethylammonium chloride C10H16ClNO edrophonium chloride (3-hydroxyphenyl)dimethylethylammonium chloride InChIKey=BXKDSDJJOVIHMX-UHFFFAOYSA-N cloruro de edrofonio chlorure d'edrophonium [Cl-].CC[N+](C)(C)c1cccc(O)c1 |
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| definition |
The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals. |
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| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_50247 |
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| label |
edrophonium chloride |
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| prefixIRI |
CHEBI:4759 |
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| prefLabel |
edrophonium chloride |
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| subClassOf |