BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

donepezil hydrochloride
Synonyms
Definitions

Donepezil hydrochloride is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

ID

http://purl.obolibrary.org/obo/CHEBI_4696

alternative term

InChIKey=XWAIAVWHZJNZQQ-UHFFFAOYSA-N

Donepezil HCl

C24H29NO3.HCl

C24H30ClNO3

1-benzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]piperidinium chloride

[H+].[Cl-].COc1cc2CC(CC3CCN(CC3)Cc3ccccc3)C(=O)c2cc1OC

(+-)-2-((1-Benzyl-4-piperidyl)methyl)-5,6-dimethoxy-1-indanone hydrochloride

InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H

Donepezil hydrochloride

1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl

definition

Donepezil hydrochloride is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

has parent hydride

http://purl.obolibrary.org/obo/CHEBI_37910

has part

http://purl.obolibrary.org/obo/CHEBI_53289

has role

http://purl.obolibrary.org/obo/CHEBI_38462

label

donepezil hydrochloride

prefixIRI

CHEBI:4696

prefLabel

donepezil hydrochloride

subClassOf

http://purl.obolibrary.org/obo/CHEBI_36807

http://purl.obolibrary.org/obo/CHEBI_3992

http://purl.obolibrary.org/obo/CHEBI_26151

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