BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

(S)-fenfluramine

Synonyms
Definitions

The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.

ID

http://purl.obolibrary.org/obo/CHEBI_439329

alternative term

(S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

(S)-fenfluramine

CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F

(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

(+)-fenfluramine

InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1

d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine

dexfenfluramine

dexfenfluramina

dextrofenfluramine

C12H16F3N

dexfenfluraminum

InChIKey=DBGIVFWFUFKIQN-VIFPVBQESA-N

definition

The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.

has role

http://purl.obolibrary.org/obo/CHEBI_50949

http://purl.obolibrary.org/obo/CHEBI_35941

http://purl.obolibrary.org/obo/CHEBI_50507

is enantiomer of

http://purl.obolibrary.org/obo/CHEBI_521051

label

(S)-fenfluramine

prefixIRI

CHEBI:439329

prefLabel

(S)-fenfluramine

subClassOf

http://purl.obolibrary.org/obo/CHEBI_5000

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