Preferred Name |
(S)-fenfluramine |
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Synonyms |
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Definitions |
The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_439329 |
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alternative term |
(S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine (S)-fenfluramine CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine (+)-fenfluramine InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1 d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine dexfenfluramine dexfenfluramina dextrofenfluramine C12H16F3N dexfenfluraminum InChIKey=DBGIVFWFUFKIQN-VIFPVBQESA-N |
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definition |
The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects. |
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has role |
http://purl.obolibrary.org/obo/CHEBI_50949 |
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is enantiomer of | ||
label |
(S)-fenfluramine |
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prefixIRI |
CHEBI:439329 |
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prefLabel |
(S)-fenfluramine |
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subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/CHEBI_439329 | CHEBI | SAME_URI | |
http://purl.obolibrary.org/obo/CHEBI_439329 | PDRO | SAME_URI | |
http://purl.obolibrary.org/obo/CHEBI_439329 | DINTO | SAME_URI | |
http://purl.obolibrary.org/obo/CHEBI_439329 | BERO | SAME_URI | |
http://purl.obolibrary.org/obo/CHEBI_439329 | DRON | SAME_URI | |
http://purl.obolibrary.org/obo/CHEBI_439329 | CHEBI | LOOM | |
http://purl.obolibrary.org/obo/CHEBI_439329 | PDRO | LOOM | |
http://purl.obolibrary.org/obo/CHEBI_439329 | DINTO | LOOM | |
http://purl.obolibrary.org/obo/CHEBI_439329 | BERO | LOOM |