BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

cefpodoxime proxetil

Synonyms
Definitions

The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pharyngitis, and sinusitis.

ID

http://purl.obolibrary.org/obo/CHEBI_3505

alternative term

[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)c1csc(N)n1)C(=O)OC(C)OC(=O)OC(C)C

(RS)-1-((isopropoxycarbonyl)oxy)ethyl (+)-(6R,7R)-7-(2-(2-amino-4-thiazolyl)-2-((Z)-methoxyimino)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

1-{[(propan-2-yloxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

C21H27N5O9S2

InChIKey=LTINZAODLRIQIX-FBXRGJNPSA-N

1-{[(propan-2-yloxy)carbonyl]oxy}ethyl 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylate

InChI=1S/C21H27N5O9S2/c1-9(2)33-21(30)35-10(3)34-19(29)15-11(6-31-4)7-36-18-14(17(28)26(15)18)24-16(27)13(25-32-5)12-8-37-20(22)23-12/h8-10,14,18H,6-7H2,1-5H3,(H2,22,23)(H,24,27)/b25-13-/t10?,14-,18-/m1/s1

cefpodoxime 1-(isopropyloxycarbonyloxy)ethyl ester

definition

The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pharyngitis, and sinusitis.

has functional parent

http://purl.obolibrary.org/obo/CHEBI_606443

http://purl.obolibrary.org/obo/CHEBI_3504

http://purl.obolibrary.org/obo/CHEBI_417636

has role

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_50266

label

cefpodoxime proxetil

prefixIRI

CHEBI:3505

prefLabel

cefpodoxime proxetil

subClassOf

http://purl.obolibrary.org/obo/CHEBI_33308

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3505 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3505 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3505 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3505 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3505 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3505 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3505 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_3505 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16203 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D000097627 MESH LOOM
http://purl.jp/bio/4/id/200906031391231990 IOBC LOOM
http://www.co-ode.org/ontologies/galen#CefpodoximeProxetil GALEN LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000455227 PDQ LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28916 NCIT LOOM
http://purl.obolibrary.org/obo/CHEBI_3505 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3505 BERO LOOM
http://stirdf.jst.go.jp/id/200907024139026736 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/96050003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148269 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-535A1 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C053267 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C28916 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0108938 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4020567 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/47835 RXNORM LOOM