loading...| Preferred Name |
colistimethate sodium |
|
| Synonyms |
|
|
| Definitions |
A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid sodium salt, commonly by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic derivative, it is used in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_34650 |
|
| alternative term |
sodium colistimethate C57H102N16Na5O28S5R pentasodium colistinmethanesulfonate Colistimethate sodium sodium colistin methanesulfonate colistimethate sodium Colistin sodium methanesulfonate [Na+].[Na+].[Na+].[Na+].[Na+].CC[C@@H](C)CCCCC(=O)N[C@@H](CCNCS([O-])(=O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCNCS([O-])(=O)=O)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCNCS([O-])(=O)=O)NC(=O)[C@H](CCNCS([O-])(=O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCNCS([O-])(=O)=O)NC1=O)[C@@H](C)O colistin sulfomethate colistimethate sodium colistinemethanesulfonate colistin sulfomethate sodium Colistin methanesulfonate |
|
| definition |
A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid sodium salt, commonly by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic derivative, it is used in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. |
|
| has functional parent | ||
| has part |
http://purl.obolibrary.org/obo/CHEBI_59663 |
|
| has role | ||
| label |
colistimethate sodium |
|
| prefixIRI |
CHEBI:34650 |
|
| prefLabel |
colistimethate sodium |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_38700 |