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BioModels Ontology
Last uploaded:
April 3, 2012
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| Preferred Name | carbidopa | |
| Synonyms |
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| Definitions |
The hydrate of 3-(3,4-dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3395 |
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| alternative term |
InChI=1S/C10H14N2O4.H2O/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4,12-14H,5,11H2,1H3,(H,15,16);1H2/t10-;/m0./s1 (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid monohydrate O.C[C@@](Cc1ccc(O)c(O)c1)(NN)C(O)=O (S)-(-)-carbidopa hydrate (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid--water (1/1) carbidopa (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate L-alpha-(3,4-dihydroxybenzyl)-alpha-hydrazinopropionic acid monohydrate carbidopa hydrate (S)-carbidopa hydrate carbidopum monohydricum InChIKey=QTAOMKOIBXZKND-PPHPATTJSA-N C10H16N2O5 (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate carbidopa monohydrate
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|
| definition |
The hydrate of 3-(3,4-dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.
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| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_48560 |
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| label |
carbidopa
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| prefixIRI |
CHEBI:3395
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| prefLabel |
carbidopa
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| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_35505 http://purl.obolibrary.org/obo/CHEBI_33566 |
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