loading...| Preferred Name |
Deflazacort |
|
| Synonyms |
|
|
| Definitions |
A synthetic glucocorticoid prodrug, with anti-inflammatory and immunomodulating properties. Upon administration, the active metabolite of deflazacort, 21-desacetyl deflazacort, binds to and activates tissue glucocorticoid receptors. This results in the inhibition of specific leukocyte functions and the inhibition of proinflammatory cytokine production. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C87230 |
|
| CAS_Registry |
14484-47-0 |
|
| Chemical_Formula |
C25H31NO6 |
|
| code |
C87230 |
|
| Contributing_Source |
FDA |
|
| definition |
A synthetic glucocorticoid prodrug, with anti-inflammatory and immunomodulating properties. Upon administration, the active metabolite of deflazacort, 21-desacetyl deflazacort, binds to and activates tissue glucocorticoid receptors. This results in the inhibition of specific leukocyte functions and the inhibition of proinflammatory cytokine production. |
|
| FDA_UNII_Code |
KR5YZ6AE4B |
|
| in_subset | ||
| label |
Deflazacort |
|
| NCI_Drug_Dictionary_ID |
802842 |
|
| PDQ_Closed_Trial_Search_ID |
802842 |
|
| PDQ_Open_Trial_Search_ID |
802842 |
|
| Preferred_Name |
Deflazacort |
|
| prefixIRI |
NCIT:C87230 |
|
| prefLabel |
Deflazacort |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0057258 |
|
| subClassOf |