loading...| Preferred Name |
Brotizolam |
|
| Synonyms |
|
|
| Definitions |
A triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C87057 |
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| CAS_Registry |
57801-81-7 |
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| Chemical_Formula |
C15H10BrClN4S |
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| code |
C87057 |
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| Contributing_Source |
FDA |
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| definition |
A triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS. |
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| FDA_UNII_Code |
5XZM1R3DKF |
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| in_subset | ||
| label |
Brotizolam |
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| Preferred_Name |
Brotizolam |
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| prefixIRI |
NCIT:C87057 |
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| prefLabel |
Brotizolam |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0054151 |
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| subClassOf |