loading...| Preferred Name | Glasdegib | |
| Synonyms |
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| Definitions |
An orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Glasdegib appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C84862 |
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| CAS_Registry |
1095173-27-5 |
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| code |
C84862 |
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| Contributing_Source |
CTRP FDA |
|
| definition |
An orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Glasdegib appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. |
|
| Display_Name |
Glasdegib |
|
| FDA_UNII_Code |
K673DMO5H9 |
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| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Glasdegib |
|
| Maps_To |
Glasdegib |
|
| NCI_META_CUI |
CL412426 |
|
| Preferred_Name |
Glasdegib |
|
| prefixIRI |
NCIT:C84862 |
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| prefLabel |
Glasdegib |
|
| Semantic_Type |
Pharmacologic Substance |
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| subClassOf |