loading...| Preferred Name | Selenium | |
| Synonyms |
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|
| Definitions |
A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C825 |
|
| Accepted_Therapeutic_Use_For |
Dandruff; Psoriasis; Seborrheic dermatitis; Tinea capitis; Tinea versicolor |
|
| ALT_DEFINITION |
A mineral that is needed by the body to stay healthy. It is being studied in the prevention and treatment of some types of cancer. Selenium is a type of antioxidant. |
|
| CAS_Registry |
7782-49-2 |
|
| CHEBI_ID |
CHEBI:27568 CHEBI:36904 |
|
| Chemical_Formula |
Se |
|
| code |
C825 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C. |
|
| Display_Name |
Selenium |
|
| FDA_UNII_Code |
H6241UJ22B |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Selenium |
|
| Legacy Concept Name |
Selenium |
|
| NCI_Drug_Dictionary_ID |
38725 |
|
| PDQ_Closed_Trial_Search_ID |
38725 |
|
| PDQ_Open_Trial_Search_ID |
38725 |
|
| Preferred_Name |
Selenium |
|
| prefixIRI |
NCIT:C825 |
|
| prefLabel |
Selenium |
|
| Semantic_Type |
Pharmacologic Substance Element, Ion, or Isotope |
|
| UMLS_CUI |
C0036581 |
|
| subClassOf |