loading...| Preferred Name |
Prasugrel Hydrochloride |
|
| Synonyms |
|
|
| Definitions |
The hydrochloride salt form of prasugrel, an orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C81571 |
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| CAS_Registry |
389574-19-0 |
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| Chemical_Formula |
C20H20FNO3S.HCl |
|
| code |
C81571 |
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| Contributing_Source |
FDA |
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| definition |
The hydrochloride salt form of prasugrel, an orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. |
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| FDA_UNII_Code |
G89JQ59I13 |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Prasugrel Hydrochloride |
|
| Legacy Concept Name |
Prasugrel_Hydrochloride |
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| Preferred_Name |
Prasugrel Hydrochloride |
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| prefixIRI |
NCIT:C81571 |
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| prefLabel |
Prasugrel Hydrochloride |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C2683417 |
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| subClassOf |