loading...| Preferred Name |
Abiraterone |
|
| Synonyms |
|
|
| Definitions |
A steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C77333 |
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| CAS_Registry |
154229-19-3 |
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| Chemical_Formula |
C24H31NO |
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| code |
C77333 |
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| Contributing_Source |
CTRP FDA |
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| definition |
A steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. |
|
| Display_Name |
Abiraterone |
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| FDA_UNII_Code |
G819A456D0 |
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| Has_Salt_Form | ||
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Abiraterone |
|
| Legacy Concept Name |
Abiraterone |
|
| Maps_To |
Abiraterone |
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| Preferred_Name |
Abiraterone |
|
| prefixIRI |
NCIT:C77333 |
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| prefLabel |
Abiraterone |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0754011 |
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| subClassOf |