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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Fondaparinux | |
| Synonyms |
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| Definitions |
A synthetic glucopyranoside with antithrombotic activity. Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C73142 |
|
| ALT_DEFINITION |
A drug used to prevent blood clots from forming inside blood vessels in the leg. It is being studied in the prevention of blood clots in some cancer patients, including women having surgery for cancer of the reproductive tract. It is a type of anticoagulant.
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| CAS_Registry |
104993-28-4
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| CHEBI_ID |
CHEBI:61033
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| Chemical_Formula |
C31H53N3O49S8
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|
| code |
C73142
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| Contributing_Source |
FDA
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|
| definition |
A synthetic glucopyranoside with antithrombotic activity. Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development.
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| FDA_UNII_Code |
J177FOW5JL
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|
| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Fondaparinux
|
|
| Legacy Concept Name |
Fondaparinux
|
|
| Preferred_Name |
Fondaparinux
|
|
| prefixIRI |
NCIT:C73142
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|
| prefLabel |
Fondaparinux
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0701492
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| subClassOf |
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