Preferred Name

Octreotide
Synonyms
Definitions

A synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.

ID

http://purl.obolibrary.org/obo/NCIT_C711

Accepted_Therapeutic_Use_For

Acromegaly; Diarrhea

ALT_DEFINITION

A drug similar to the naturally occurring growth hormone inhibitor somatostatin. Octreotide is used to treat diarrhea and flushing associated with certain types of tumors.

CAS_Registry

83150-76-9

CHEBI_ID

CHEBI:7726

Chemical_Formula

C49H66N10O10S2

code

C711

Contributing_Source

CTRP

FDA

definition

A synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.

Display_Name

Octreotide

FDA_UNII_Code

RWM8CCW8GP

Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C2402

http://purl.obolibrary.org/obo/NCIT_C53447

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C177537

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978

http://purl.obolibrary.org/obo/NCIT_C128784

http://purl.obolibrary.org/obo/NCIT_C157711

http://purl.obolibrary.org/obo/NCIT_C157712

Is_Value_For_GDC_Property

http://purl.obolibrary.org/obo/NCIT_C1909

label

Octreotide

Legacy Concept Name

Octreotide

Maps_To

Octreotide

Preferred_Name

Octreotide

prefixIRI

NCIT:C711

prefLabel

Octreotide

PubMedID_Primary_Reference

16917205

Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance

UMLS_CUI

C0028833

subClassOf

http://purl.obolibrary.org/obo/NCIT_C62799

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/OMIT_0016068 OMIT LOOM
http://purl.obolibrary.org/obo/CHEBI_7726 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7726 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_7726 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7726 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7726 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_7726 DRON LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028833 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D015282 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_77260 FIDEO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018774 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/ATC/H01CB02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU035158 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Octreotide GALEN LOOM
http://purl.obolibrary.org/obo/dinto_DB00104 DINTO LOOM
http://purl.bioontology.org/ontology/RCD/he6.. RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147950 NDFRT LOOM
https://go.drugbank.com/drugs/DB00104 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.641.650 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00104 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8891 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/7617 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4019864 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/002107 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015282 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C711 NCIT LOOM
http://purl.jp/bio/4/id/200906025800883074 IOBC LOOM
http://stirdf.jst.go.jp/id/200907079083884180 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP97954-9 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/4007-0092 CRISP LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/109053000 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.345.566.650 RH-MESH LOOM