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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Novobiocin | |
| Synonyms |
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| Definitions |
An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other aminocoumarin antibiotics, inhibits bacterial DNA synthesis by targeting at the bacteria DNA gyrase and the related enzyme DNA topoisomerase IV. This antibiotic was used to treat infections by gram-positive bacteria. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C705 |
|
| ALT_DEFINITION |
An antibiotic drug used to treat infection.
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| CAS_Registry |
303-81-1
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| CHEBI_ID |
CHEBI:28368
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| Chemical_Formula |
C31H36N2O11
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|
| code |
C705
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| Contributing_Source |
FDA
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|
| definition |
An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other aminocoumarin antibiotics, inhibits bacterial DNA synthesis by targeting at the bacteria DNA gyrase and the related enzyme DNA topoisomerase IV. This antibiotic was used to treat infections by gram-positive bacteria.
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| FDA_UNII_Code |
17EC19951N
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Novobiocin
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|
| Legacy Concept Name |
Novobiocin
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| NCI_Drug_Dictionary_ID |
39195
|
|
| NSC Number |
2382
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| PDQ_Closed_Trial_Search_ID |
39195
|
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| PDQ_Open_Trial_Search_ID |
39195
|
|
| Preferred_Name |
Novobiocin
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|
| prefixIRI |
NCIT:C705
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| prefLabel |
Novobiocin
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
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| UMLS_CUI |
C0028458
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| subClassOf |
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