loading...| Preferred Name | Micafungin Sodium | |
| Synonyms |
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|
| Definitions |
The sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan. By preventing the synthesis of 1,3-beta-D-glucan, the cell wall is weakened which leads to osmotic lysis and eventually fungal cell death. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C66145 |
|
| CAS_Registry |
208538-73-2 |
|
| Chemical_Formula |
C56H70N9O23S.Na |
|
| code |
C66145 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
The sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan. By preventing the synthesis of 1,3-beta-D-glucan, the cell wall is weakened which leads to osmotic lysis and eventually fungal cell death. |
|
| Display_Name |
Micafungin Sodium |
|
| FDA_UNII_Code |
IS1UP79R56 |
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Micafungin Sodium |
|
| Legacy Concept Name |
Micafungin_Sodium |
|
| NCI_Drug_Dictionary_ID |
635524 |
|
| PDQ_Closed_Trial_Search_ID |
635524 |
|
| PDQ_Open_Trial_Search_ID |
635524 |
|
| Preferred_Name |
Micafungin Sodium |
|
| prefixIRI |
NCIT:C66145 |
|
| prefLabel |
Micafungin Sodium |
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| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C1576821 |
|
| subClassOf |